Endocrine Hormone MCQ collection with solutions

 
Endocrinology – Hormones MCQS practices for all medicos with solutions
 
 
(Hormone acts soon if the cell has receptors for the hormone, you will become soon successful and beautiful like moon if you are the acceptor of whom who performed the miracle of moon)
 
 

1. It acts as a first messenger:
2. a) c-AMP b) c-GMP
3. c) calmodulin d) calcium
4. e) calcitonin

2. The enzyme required for the synthesis of c-AMP is:
3. a) tyrosine kinase b) phospholipase C
4. c) adenylate cyclase d) G-Protein
5. e) ATPase

3. An 11 years old patient comes to doctor with obesity and dwarfism. He needs the administration of:
4. a) insulin b) growth hormone
5. c) glucagon d) testosterone
6. e) catecholamines

4. Find the mis-match.
5. a) pancreas : somatostatin
6. b) thyroid gland : calcitonin
7. c) Anterior pituitary : thyrotropin releasing hormone
8. d) adrenal medulla : catecholamines
9. e) adrenal cortex : mineralocorticoids

5. Testosterone formation in the fetus is stimulated by:
6. a) FSH b) LH
7. c) both a & b d) HCG hormone
8. e) anti mullerian hormone

6. It has receptors in the cytoplasm:
7. a) insulin b) glucagon
8. c) cortisol d) growth hormone
9. e) oxytocin

7. The commonest cause of diabetes mellitus is:
8. a) carbohydrate diet b) congenital absence of insulin
9. c) obesity d) pancreatic atrophy
10. e) lack of exercise
11. Oxytocin is secreted by:
12. a) supra optic nuclei b) para optic nuclei
13. c) para ventricular nuclei d) posterior pituitary
14. e) uterus

9. The most appropriate option that represents an exocrine gland:
10. a) duct b) blood
11. c) hormone d) secretory vesicle

10. It may be called as master gland:
11. a) hypothalamus b) pituitary gland
12. c) thyroid gland d) pancreas
13. e) adrenal gland

11. All are the dissimilarities of hormones with enzymes except:
12. a) they are poured into blood
13. b) they are not used up during the reaction
14. c) they are produced by one organ and act on the other
15. d) they all are not protein in nature.

12. It has receptors in the nucleus:
13. a) FSH b) TSH
14. c) calcitonin d) thyroxin

13. Thyroid hormones and catecholamines are derived from:
14. a) alcohol b) cholesterol
15. c) tryptofan d) tyrosine
16. e) glycine

14. The precursor for steroid hormones is:
15. a) alcohol b) cholesterol
16. c) hyroxy cholesterol d) hyroxy steroids
17. e) lipids

15. It does not match others in the list:
16. a) FSH b) estrogen
17. c) progesterone d) testosterone
18. e) aldosterone
19. Growth hormone:
20. a) double polypeptide
21. b) glycoprotein
22. c) requires insulin for its growth promoting action
23. d) requires IGF for its growth promoting action
24. e) decreases gluconeogenesis

17. The concentration of with hormone will increase if the hypothalamus is damaged:
18. a) ACTH b) FSH
19. c) TSH d) LH
20. e) prolactin

18. All of the following hormones are anabolic to protein metabolism except:
19. a) growth hormone
20. b) thyroid hormones in small physiological doses
21. c) insulin
22. d) cortisol in extra hepatic tissues
23. e) testosterone

19. All of the following hormones have their actions on mammary gland except:
20. a) estrogen b) progesterone
21. c) prolactin d) growth hormone
22. e) LH

• Milk ejection during suckling is caused by:

1. a) prolactin b) LH
2. c) oxytocin d) progesterone
3. e) somatomammotroph

21. It has receptors on cell membrane
22. a) T₃ b) T₄
23. c) TSH d) aldosterone
24. e) testosterone

• Testosterone formation in the adults is stimulated by:

1. a) FSH b) LH
2. c) growth hormone d) inhibin
3. e) N.O.T

• It is indispensable for the ovulation to occur

1. a) FSH b) LH
2. c) prolactin d) estrogen
3. e) progesterone

• ADH and oxytocin require _______ for their transport from hypothalamus to posterior pituitary.

1. a) albumin b) globulin
2. c) plasma proteins d) neurophysin
3. e) freely in water

• ADH:

1. a) acts on collecting duct to reabsorb water
2. b) increases blood volume
3. c) relaxes smooth muscles
4. d) released from posterior pituitary
5. e) increases intracellular Ca⁺⁺ concentration

• Growth hormone:

1. a) increases bone growth b) decreases TG synthesis
2. c) increases protein synthesis d) decreases intestinal Ca⁺⁺ absorption
3. e) increases blood glucose

• It is known as love hormone:

1. a) oxytocin b) estrogen
2. c) progesterone d) prolactin
3. e) LH

• Thyroid glands contain large quantities of a protein called:

1. a) thyroprotein b) thyroalbumin
2. c) thyroglobulin d) thyrotyrosine
3. e) thyroprealbumin

• All are necessary for the formation of thyroid hormones except:

1. a) iodide trapping b) coupling of iodotyrosines
2. c) iodination of tyrosine d) reduction of iodide
3. e) thyroperoxidase

• The most powerful and active thyroid hormone is:

1. a) T₃ b) T₄
2. c) reverse T₃ d) TSH
3. e) calcitonin

31. All of the following hormones are hyperglycemic except:
32. a) growth hormone b) glucagon
33. c) cortisol d) thyroid hormones
34. e) ACTH

• Parathormone:

1. a) increases PO₄ level b) decreases Ca⁺⁺ level
2. c) increases P absorption d) decreases Ca⁺⁺ excretion
3. e) increases osteoblastic activity

• Find the incorrect statement:

1. a) ANP is secreted from kidneys
2. b) ACTH stimulates cortisol
3. c) aldosterone secretion is stimulated by potassium an aldosterone
4. d) corticotropin releasing hormone is secreted from hypothalamus
5. e) N.O.T

• A patient comes to doctor with low blood pressure and polyuria. He needs the administration of:

1. a) mineralocorticoids b) glucocorticoids
2. c) ADH c) insulin
3. e) ACTH

• Insulin receptors consist of:

1. a) α-chain b) β-chain
2. c) α & β chains d) 1 α & 2 β chains
3. e) 2 α & 2 β chains

• Insulin:

1. a) acts through tyrosine kinase pathway
2. b) can be taken orally in case of diabetes mellitus.
3. c) has half life of about 6 min.
4. d) is secreted by β cells of pancreas
5. e) is hypoglycemic hormone

• Insulin increases all of the followings except:

1. a) protein synthesis b) TG synthesis
2. c) glycogenesis d) gluconeogenesis
3. e) convertion of pyruvate to acetyl CoA

• Glucagon increases:

1. a) glycogenesis b) TG synthesis
2. c) excretion of glucose d) protein synthesis
3. e) force of contraction of heart

• The major free circulating adrenocorticoid hormone in human is:

1. a) aldosterone b) cortisol
2. c) corticosterone d) androgens
3. e) cortisone

• All of the following hormones release androgens except:

1. a) adrenal gland b) testis
2. c) ovary d) mammary gland
3. e) placenta

41. Total amino acids in insulin molecule are:
42. a) 49 b) 50
43. c) 51 d) 52
44. e) 55

• Find the incorrect statement:

1. a) hypothalamus is endocrine gland
2. b) GIT wall is exocrine
3. c) pancreas is endocrine as well as exocrine
4. d) liver is exocrine gland
5. e) parotid is exocrine gland

• Aldosterone:

1. a) is secreted from zona glomerulosa
2. b) increases blood volume
3. c) antagonizes the effect of ANP
4. d) increases reabsorption of chlorides
5. e) increases K⁺ absorption

• The main cause of baldness in men is:

1. a) cholesterol b) testosterone
2. c) vitamin deficiency d) thyroid hormones
3. e) cortisol

• Catecholamines:

1. a) Ca⁺⁺ acts as second messenger on binding with β receptors
2. b) c-AMP acts as second messenger on binding with α receptors
3. c) nor epinephrine is chiefly synthesized by adrenal medulla
4. d) epinephrine inhibits insulin release
5. e) in muscles epinephrine causes glycogenesis

• The immediate precursor of testosterone is:

1. a) cholesterol b) pregnenolone
2. c) androstenedione d) progesterone
3. e) 17-hydroxyprogesterone

• Estrogen

1. a) increases the size of female genital organs
2. b) the most active form is β estradiol
3. c) causes appearance of secondary sexual characters
4. d) used as contraceptive
5. e) causes development of alveolar system of breasts

• Progesterone:

1. a) secreted from ovary b) secreted from corpus luteum
2. c) causes menstruation d) causes changes in endometrium
3. e) the immediate precursor is pregnenolone

• It causes contraction of gall bladder and emptying of bile

1. a) gastrin b) cholecystokinin
2. c) motilin d) secretin
3. e) GIP

• After menopause there is increase in:

1. a) FSH b) LH
2. c) both a & b d) estrogen
3. e) progesterone

51. gonadotropic hormones are_______ in nature
52. a) glycoprotein b) protein
53. c) steroid d) amino acid derivatives

• It uses phospholipase C pathway

1. a) oxytocin b) growth hormone
2. c) parathormone d) glucagon
3. e) ACTH

• Insulin increases:

1. a) gluconeogenesis b) amino acid formation
2. c) glycogenolysis d) lipolysis
3. e) glycogenesis

• FSH secretion is inhibited by:

1. a) inhibin b) LH
2. c) progesterone d) somatostatin
3. e) dihydrotestosterone

• _______ increase the requirement of vitamins:

1. a) adrenal androgens b) testosterone
2. c) thyroid hormones c) parathormone
3. e) growth hormone

• Kidneys secrete:

1. a) aldosterone b) angiotensin 1
2. c) angiotensin 2 d) renin
3. e) A.O.T

• Cortisol:

1. a) decreases lipolysis
2. b) increases inflammation
3. c) decreases permeability of capillary membrane
4. d) increases extra hepatic protein synthesis
5. e) decreases stability of lysosomal membrane

• A patient comes to doctor suffering from leg trauma and excess inflammation. He needs the administration of:

1. a) growth hormone b) glucagon
2. c) insulin d) cortisol
3. e) aldosterone

• Antimullerian hormone is secreted by:

1. a) interstitial cells of leydig b) GIT wall
2. c) ovary d) sustenticular cells of sertoli
3. e) prostate gland

• Pregnancy test is based on the presence of ______ in urine

1. a) FSH b) LH
2. c) HCG d) estrogen
3. e) progesterone

61. All are the stimulus for glucagon secretion except:
62. a) stress b) hypoglycemia
63. c) starvation d) exercise
64. e) somatostatin

• Find the incorrect statement:

1. a) glucagon does not affect muscles
2. b) seminal vesicles are exocrine glands
3. c) TSH converts columnar thyroid cells to cuboidal
4. d) The number of receptors vary within minutes
5. e) Growth hormone increases insulin secretion

• Questions 63 – 80

• Select from the terms below:

1. A) Acromegaly B) Addison’s disease
2. C) Conn’s syndrome D) Adrenogenital syndrome
3. E) Cushing’s syndrome F) Diabetes insipidus
4. G) Goiter H) Hypothyroidism
5. I) Hyperthyroidism J) Cretinism
6. K) Osteoporosis L) Panhypopituitarism
7. M) Type 1 diabetes N) Type 2 diabetes
8. O) N.O.T

• The enlargement of thyroid gland

• Loss of function of vasopressin

• Characterized by hyperkalemia

• Growth hormone deficiency in children

• Excess growth hormone in adults

• Tumors of zona glomerulasa cause

• Administration of insulin is the treatment

• Characterized by myxedema, cold intolerance

71. Characterized by torso buffalo

• Lack of thyroid hormones during childhood

• Characterized by thickening of hands, feet, protrusion of jaws but the height remains normal

• Total lack of posterior pituitary hormones

• Old age disease due to the Vitamin C and estrogen deficiency

• Insulin resistance by the target cells

• TSH is elevated.

• Excess cortisol

• In pre pubertal males causes enlargement of sex organs

• Characterized by somnolence.

 
Answer Key