National Guideline Rabies Prophylaxis in Nepal 2019

This Guideline of National Guideline Rabies Prophylaxis in Nepal 2019 is published by Department of Health Services department of Health Services, Epidemiology and Disease Control Division Teku, Kathmandu Nepal.

Rabies is a disease with the highest documented case-fatality rate, close to 100%. Rabies has terrifi ed man since antiquity. Rural populations are disproportionately affected, experiencing the greatest burden with the least access to affordable preventive treatment.

In 2015, World Health Organization (WHO) and World Organization for Animal Health (OIE), in collaboration with Food and Agriculture Organization (FAO) and the Global Alliance for Rabies Control (GARC), organized a global rabies conference in Geneva, bringing together partners and stakeholders in veterinary and human health, government and the private sectors, and launched the Global framework for the elimination of dog-mediated human rabies, outlining the commitment and actions required to achieve a common goal of zero human rabies deaths by 2030, worldwide.

Since the launch of the Global framework, WHO has been working with partners to prepare a global strategic plan to end human deaths from dog-mediated rabies by 2030. This includes a country-centric approach, with international partners (WHO, FAO, OIE and GARC) to support, empower and catalyze national entities to control and eliminate rabies.

This national guideline on human rabies prophylaxis have been prepared in the light of new recommendations made by the WHO Expert Consultation on Rabies in 2017, which will improve patient compliance to PEP regimen and make rational use of rabies vaccine and immunoglobulin.

National Guideline Rabies Prophylaxis in Nepal 2019 contains following topics or chapters

1.. Introduction
2. Rabies Virus
3. Transmission
4. Disease
5. Diagnosis
5.1. Standard Case Classifi cation
5.2. Differential Diagnosis
5.3. Laboratory Diagnosis
6. Post Exposure Prophylaxis (PEP)
6.1. Indication
6.2. WHO Classifi cation of Exposures
6.3. PEP by Category of Exposure
6.4. PEP Components
6.4.1. Local Wound Treatment
6.4.2. Rabies Immunoglobulins
6.4.3. Rabies Vaccines
6.5. PEP for Re Exposure
6.6. PEP in Special Groups
6.7. Points for Consideration
7. Management of Patients with Rabies
8. Pre-Exposure Prophylaxis (PrEP)