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Role of Zinc in childhood diarrhea management: a case of Nepal

Role of Zinc in childhood diarrhea management: a case of Nepal

Published on:December 2016
Journal of Pharmacy Practice and Community Medicine, 2017; 3(1):34-36
Brief Report | doi:10.5530/jppcm.2017.1.8

Authors and affiliation (s):

Kadir Alam1*, Arjun Poudel2, Subish Palaian3, Bhawesh Koirala1, Pathiyil Ravi Shankar4
1Department of Clinical Pharmacology and Therapeutics, B.P. Koirala Institute of Health Sciences, Dharan, NEPAL.
2School of Clinical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, AUSTRALIA.
3Department of Pharmacy Practice, College of Pharmacy, Gulf Medical University, Ajman, UAE.
4Department of Pharmacology, Xavier University School of Medicine, Aruba, Kingdom of the NETHERLENDS.


Diarrhea is one of the leading causes of death among children less than five years of age around the world accounting for about two million child deaths annually. One of the recent strategies made to minimize the diarrhea associated mortality in children involves the use of oral zinc in diarrhea management. The inadequacy of dietary zinc uptake is exacerbated by the net loss of zinc during diarrhea. Zinc is enlisted in WHO essential drug list under medicine for diarrhea where it is indicated in acute diarrhea as an adjunct to oral rehydration salts. Zinc is usually well tolerated. It is necessary to explore public health applications, using zinc either as a preventive measure in children or therapeutically for diarrhea.
Key words: Diarrhea, Dehydration, Mortality, Nepal, Zinc.

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